node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BC_0099 | BC_0100 | BC_0099 | BC_0100 | Transcriptional regulator ctsR; Belongs to the CtsR family. | ClpC ATPase. | 0.994 |
BC_0099 | BC_0102 | BC_0099 | BC_0102 | Transcriptional regulator ctsR; Belongs to the CtsR family. | Negative regulator of genetic competence clpC/mecB; Belongs to the ClpA/ClpB family. | 0.973 |
BC_0099 | BC_0105 | BC_0099 | BC_0105 | Transcriptional regulator ctsR; Belongs to the CtsR family. | Hypothetical Membrane Associated Protein. | 0.727 |
BC_0099 | disA | BC_0099 | BC_0104 | Transcriptional regulator ctsR; Belongs to the CtsR family. | DNA-binding protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | 0.522 |
BC_0099 | mcsB | BC_0099 | BC_0101 | Transcriptional regulator ctsR; Belongs to the CtsR family. | Arginine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | 0.980 |
BC_0099 | radA | BC_0099 | BC_0103 | Transcriptional regulator ctsR; Belongs to the CtsR family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.746 |
BC_0100 | BC_0099 | BC_0100 | BC_0099 | ClpC ATPase. | Transcriptional regulator ctsR; Belongs to the CtsR family. | 0.994 |
BC_0100 | BC_0102 | BC_0100 | BC_0102 | ClpC ATPase. | Negative regulator of genetic competence clpC/mecB; Belongs to the ClpA/ClpB family. | 0.986 |
BC_0100 | BC_0105 | BC_0100 | BC_0105 | ClpC ATPase. | Hypothetical Membrane Associated Protein. | 0.710 |
BC_0100 | disA | BC_0100 | BC_0104 | ClpC ATPase. | DNA-binding protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | 0.686 |
BC_0100 | ispD | BC_0100 | BC_0106 | ClpC ATPase. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.461 |
BC_0100 | mcsB | BC_0100 | BC_0101 | ClpC ATPase. | Arginine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | 0.999 |
BC_0100 | radA | BC_0100 | BC_0103 | ClpC ATPase. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.712 |
BC_0102 | BC_0099 | BC_0102 | BC_0099 | Negative regulator of genetic competence clpC/mecB; Belongs to the ClpA/ClpB family. | Transcriptional regulator ctsR; Belongs to the CtsR family. | 0.973 |
BC_0102 | BC_0100 | BC_0102 | BC_0100 | Negative regulator of genetic competence clpC/mecB; Belongs to the ClpA/ClpB family. | ClpC ATPase. | 0.986 |
BC_0102 | BC_0105 | BC_0102 | BC_0105 | Negative regulator of genetic competence clpC/mecB; Belongs to the ClpA/ClpB family. | Hypothetical Membrane Associated Protein. | 0.572 |
BC_0102 | disA | BC_0102 | BC_0104 | Negative regulator of genetic competence clpC/mecB; Belongs to the ClpA/ClpB family. | DNA-binding protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | 0.683 |
BC_0102 | ispD | BC_0102 | BC_0106 | Negative regulator of genetic competence clpC/mecB; Belongs to the ClpA/ClpB family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.492 |
BC_0102 | mcsB | BC_0102 | BC_0101 | Negative regulator of genetic competence clpC/mecB; Belongs to the ClpA/ClpB family. | Arginine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | 0.999 |
BC_0102 | radA | BC_0102 | BC_0103 | Negative regulator of genetic competence clpC/mecB; Belongs to the ClpA/ClpB family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.821 |