STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutIImidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (423 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 
 0.999
hutH
Histidine ammonia-lyase; Belongs to the PAL/histidase family.
 
  
 0.999
rocD
Ornithine aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde.
   
  
 0.716
hutP
Hut operon positive regulatory protein; Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization; Belongs to the HutP family.
 
  
 0.706
rocF
Arginase; Belongs to the arginase family.
  
  
 0.685
rocA
Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. RocA subfamily.
   
  
 0.635
pyrR
Uracil phosphoribosyltransferase; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
      
 0.602
ald
Alanine dehydrogenase; Belongs to the AlaDH/PNT family.
      
 0.528
ald-2
Alanine dehydrogenase; Belongs to the AlaDH/PNT family.
      
 0.508
speB
Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.
  
  
 0.506
Your Current Organism:
Bacillus cereus ATCC 14579
NCBI taxonomy Id: 226900
Other names: B. cereus ATCC 14579, Bacillus cereus (strain ATCC 14579 / DSM 31)
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