node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BC_0380 | BC_4251 | BC_0380 | BC_4251 | L-fuculose phosphate aldolase. | 5-methyltetrahydrofolate--homocysteine methyltransferase. | 0.571 |
BC_0380 | drdI | BC_0380 | BC_0379 | L-fuculose phosphate aldolase. | Methylthioribose salvage protein; Catalyzes the isomerization of 5-deoxy-alpha-D-ribose 1- phosphate to 5-deoxy-D-ribulose 1-phosphate, as part of a 5-deoxyribose salvage pathway that recycles this toxic radical SAM enzyme by-product to mainstream metabolites. | 0.990 |
BC_0380 | metH | BC_0380 | BC_4250 | L-fuculose phosphate aldolase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.491 |
BC_0380 | mtnA | BC_0380 | BC_4032 | L-fuculose phosphate aldolase. | Methylthioribose salvage protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.837 |
BC_0380 | mtnD | BC_0380 | BC_4039 | L-fuculose phosphate aldolase. | 2-hydroxy-3-oxo-5-methylthiopent-2-enoate oxidase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.440 |
BC_0380 | mtnK | BC_0380 | BC_0378 | L-fuculose phosphate aldolase. | 5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.947 |
BC_4251 | BC_0380 | BC_4251 | BC_0380 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | L-fuculose phosphate aldolase. | 0.571 |
BC_4251 | BC_5404 | BC_4251 | BC_5404 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | Homoserine dehydrogenase. | 0.959 |
BC_4251 | drdI | BC_4251 | BC_0379 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | Methylthioribose salvage protein; Catalyzes the isomerization of 5-deoxy-alpha-D-ribose 1- phosphate to 5-deoxy-D-ribulose 1-phosphate, as part of a 5-deoxyribose salvage pathway that recycles this toxic radical SAM enzyme by-product to mainstream metabolites. | 0.574 |
BC_4251 | metH | BC_4251 | BC_4250 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
BC_4251 | mtnA | BC_4251 | BC_4032 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | Methylthioribose salvage protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.857 |
BC_4251 | mtnB | BC_4251 | BC_4038 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | Methylthioribose salvage protein (putative aldolase); Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). | 0.616 |
BC_4251 | mtnD | BC_4251 | BC_4039 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | 2-hydroxy-3-oxo-5-methylthiopent-2-enoate oxidase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.857 |
BC_4251 | mtnK | BC_4251 | BC_0378 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | 5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.722 |
BC_4251 | mtnK-2 | BC_4251 | BC_4033 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | 5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.743 |
BC_4251 | mtnW | BC_4251 | BC_4036 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | Ribulose bisphosphate carboxylase large chain; Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P); Belongs to the RuBisCO large chain family. Type IV subfamily. | 0.794 |
BC_5404 | BC_4251 | BC_5404 | BC_4251 | Homoserine dehydrogenase. | 5-methyltetrahydrofolate--homocysteine methyltransferase. | 0.959 |
BC_5404 | metH | BC_5404 | BC_4250 | Homoserine dehydrogenase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.972 |
BC_5404 | mtnA | BC_5404 | BC_4032 | Homoserine dehydrogenase. | Methylthioribose salvage protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.846 |
BC_5404 | mtnB | BC_5404 | BC_4038 | Homoserine dehydrogenase. | Methylthioribose salvage protein (putative aldolase); Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). | 0.728 |