node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
eno | lrgB | BC_5135 | BC_5438 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Murein hydrolase export regulator; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | 0.424 |
eno | lytT | BC_5135 | BC_5440 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Autolysin response regulator; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | 0.592 |
lrgA | lrgB | BC_5439 | BC_5438 | Murein hydrolase exporter; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidA/LrgA family. LrgA subfamily. | Murein hydrolase export regulator; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | 0.998 |
lrgA | lytS | BC_5439 | BC_5441 | Murein hydrolase exporter; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidA/LrgA family. LrgA subfamily. | Autolysin sensor kinase; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | 0.934 |
lrgA | lytT | BC_5439 | BC_5440 | Murein hydrolase exporter; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidA/LrgA family. LrgA subfamily. | Autolysin response regulator; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | 0.929 |
lrgB | eno | BC_5438 | BC_5135 | Murein hydrolase export regulator; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.424 |
lrgB | lrgA | BC_5438 | BC_5439 | Murein hydrolase export regulator; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | Murein hydrolase exporter; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidA/LrgA family. LrgA subfamily. | 0.998 |
lrgB | lytS | BC_5438 | BC_5441 | Murein hydrolase export regulator; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | Autolysin sensor kinase; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | 0.911 |
lrgB | lytT | BC_5438 | BC_5440 | Murein hydrolase export regulator; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | Autolysin response regulator; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | 0.943 |
lytS | lrgA | BC_5441 | BC_5439 | Autolysin sensor kinase; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | Murein hydrolase exporter; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidA/LrgA family. LrgA subfamily. | 0.934 |
lytS | lrgB | BC_5441 | BC_5438 | Autolysin sensor kinase; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | Murein hydrolase export regulator; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | 0.911 |
lytS | lytT | BC_5441 | BC_5440 | Autolysin sensor kinase; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | Autolysin response regulator; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | 0.999 |
lytT | eno | BC_5440 | BC_5135 | Autolysin response regulator; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.592 |
lytT | lrgA | BC_5440 | BC_5439 | Autolysin response regulator; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | Murein hydrolase exporter; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidA/LrgA family. LrgA subfamily. | 0.929 |
lytT | lrgB | BC_5440 | BC_5438 | Autolysin response regulator; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | Murein hydrolase export regulator; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | 0.943 |
lytT | lytS | BC_5440 | BC_5441 | Autolysin response regulator; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | Autolysin sensor kinase; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. | 0.999 |