node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BC_3603 | folE | BC_3603 | BC_1511 | Anaerobic ribonucleoside-triphosphate reductase. | GTP cyclohydrolase I. | 0.801 |
BC_3603 | queE | BC_3603 | BC_1343 | Anaerobic ribonucleoside-triphosphate reductase. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.834 |
BC_3994 | queE | BC_3994 | BC_1343 | Exopolyphosphatase. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.451 |
folE | BC_3603 | BC_1511 | BC_3603 | GTP cyclohydrolase I. | Anaerobic ribonucleoside-triphosphate reductase. | 0.801 |
folE | queC | BC_1511 | BC_1341 | GTP cyclohydrolase I. | Aluminum resistance protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.438 |
folE | queD | BC_1511 | BC_1342 | GTP cyclohydrolase I. | 6-pyruvoyl tetrahydrobiopterin synthase. | 0.993 |
folE | queE | BC_1511 | BC_1343 | GTP cyclohydrolase I. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.678 |
folE | queF | BC_1511 | BC_1344 | GTP cyclohydrolase I. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.456 |
guaA | purF | BC_0296 | BC_0330 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.811 |
guaA | queD | BC_0296 | BC_1342 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 6-pyruvoyl tetrahydrobiopterin synthase. | 0.494 |
guaA | queE | BC_0296 | BC_1343 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.501 |
guaA | queF | BC_0296 | BC_1344 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.537 |
guaA | rsmB | BC_0296 | BC_3863 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 16S rRNA m(5)C 967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.547 |
purF | guaA | BC_0330 | BC_0296 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.811 |
purF | queE | BC_0330 | BC_1343 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.406 |
queC | folE | BC_1341 | BC_1511 | Aluminum resistance protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | GTP cyclohydrolase I. | 0.438 |
queC | queD | BC_1341 | BC_1342 | Aluminum resistance protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 6-pyruvoyl tetrahydrobiopterin synthase. | 0.998 |
queC | queE | BC_1341 | BC_1343 | Aluminum resistance protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
queC | queF | BC_1341 | BC_1344 | Aluminum resistance protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.998 |
queD | folE | BC_1342 | BC_1511 | 6-pyruvoyl tetrahydrobiopterin synthase. | GTP cyclohydrolase I. | 0.993 |