Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BC_1925Amine oxidase, flavin-containing. (478 aa)    
Predicted Functional Partners:
BC_4251
5-methyltetrahydrofolate--homocysteine methyltransferase.
   
 
 0.918
mtnD
2-hydroxy-3-oxo-5-methylthiopent-2-enoate oxidase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
  
 
 0.917
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
  0.917
BC_4034
Nitrilase.
    
 0.913
BC_1285
Aldehyde dehydrogenase (NAD(P)+); Belongs to the aldehyde dehydrogenase family.
   
 0.910
asnB-2
Asparagine synthetase, glutamine-hydrolyzing.
   
 
  0.909
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
 
 0.909
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
   
 
 0.908
BC_2832
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.908
BC_3555
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.908
Your Current Organism:
Bacillus cereus ATCC 14579
NCBI taxonomy Id: 226900
Other names: B. cereus ATCC 14579, Bacillus cereus (strain ATCC 14579 / DSM 31)
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