proC-3 protein (Bacillus cereus ATCC 14579) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

proC-3

Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa)

Predicted Functional Partners:

BC_0906

0.979

BC_0905

0.906

BC_2834

0.906

BC_2835

0.906

rocA

0.903

BC_2171

0.903

proB

0.903

BC_2337

0.900

BC_4233

0.900

BC_4663

0.900

Your Current Organism:

Bacillus cereus ATCC 14579

NCBI taxonomy Id: 226900
Other names: B. cereus ATCC 14579, Bacillus cereus (strain ATCC 14579 / DSM 31)

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BC_0905	BC_0906	BC_0905	BC_0906	Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Displays no proline racemase activity.	Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family.	0.996
BC_0905	BC_2171	BC_0905	BC_2171	Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Displays no proline racemase activity.	Proline iminopeptidase.	0.900
BC_0905	BC_2337	BC_0905	BC_2337	Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Displays no proline racemase activity.	Proline iminopeptidase.	0.900
BC_0905	BC_2834	BC_0905	BC_2834	Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Displays no proline racemase activity.	Proline racemase.	0.936
BC_0905	BC_2835	BC_0905	BC_2835	Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Displays no proline racemase activity.	Proline racemase; Belongs to the proline racemase family.	0.915
BC_0905	BC_4233	BC_0905	BC_4233	Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Displays no proline racemase activity.	Prolyl 4-hydroxylase alpha subunit.	0.900
BC_0905	BC_4663	BC_0905	BC_4663	Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Displays no proline racemase activity.	Proline iminopeptidase.	0.900
BC_0905	proC-3	BC_0905	BC_3109	Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Displays no proline racemase activity.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.906
BC_0906	BC_0905	BC_0906	BC_0905	Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family.	Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Displays no proline racemase activity.	0.996
BC_0906	BC_2171	BC_0906	BC_2171	Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family.	Proline iminopeptidase.	0.901
BC_0906	BC_2337	BC_0906	BC_2337	Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family.	Proline iminopeptidase.	0.900
BC_0906	BC_2834	BC_0906	BC_2834	Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family.	Proline racemase.	0.966
BC_0906	BC_2835	BC_0906	BC_2835	Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family.	Proline racemase; Belongs to the proline racemase family.	0.969
BC_0906	BC_4233	BC_0906	BC_4233	Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family.	Prolyl 4-hydroxylase alpha subunit.	0.911
BC_0906	BC_4663	BC_0906	BC_4663	Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family.	Proline iminopeptidase.	0.903
BC_0906	proB	BC_0906	BC_2975	Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family.	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.469
BC_0906	proC-3	BC_0906	BC_3109	Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.979
BC_2171	BC_0905	BC_2171	BC_0905	Proline iminopeptidase.	Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Displays no proline racemase activity.	0.900
BC_2171	BC_0906	BC_2171	BC_0906	Proline iminopeptidase.	Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family.	0.901
BC_2171	BC_2337	BC_2171	BC_2337	Proline iminopeptidase.	Proline iminopeptidase.	0.922

page 1 of 4

Server load: low (30%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2023

Credits

Access

Info

About