Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
KIH83016.12-oxo-hepta-3-ene-1,7-dioic acid hydratase; Isu;Aromatic_amino_acid_degradation isu;4-Hydroxyphenylacetic_acid_catabolic_pathway isu;Benzoate_transport_and_degradation_cluster isu;Central_meta- cleavage_pathway_of_aromatic_compound_degr adation. (267 aa)    
Predicted Functional Partners:
KIH83017.1
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Icw(5);Aromatic_amino_acid_degradation icw(6);4-Hydroxyphenylacetic_acid_catabolic_pathway; Belongs to the HpcH/HpaI aldolase family.
 
 0.999
KIH83014.1
5-carboxymethyl-2-hydroxymuconate delta-isomerase; Icw(1);Aromatic_amino_acid_degradation icw(1);4-Hydroxyphenylacetic_acid_catabolic_pathway icw(2);Central_meta- cleavage_pathway_of_aromatic_compound_d egradation.
 
  
 0.994
KIH83013.1
3,4-dihydroxyphenylacetate 2,3-dioxygenase; Isu;Aromatic_dioxygenase_mess isu;Aromatic_Amin_Catabolism icw(5);Aromatic_amino_acid_degradation icw(5);4-Hydroxyphenylacetic_acid_catabolic_pathway icw(3);Central_meta- cleavage_pathway_of_aromatic_compound_d egradation isu;Dioxygenases_.
 
  
 0.993
KIH83011.1
Icw(2);Aromatic_amino_acid_degradation icw(3);Aromatic_amino_acid_degradation icw(2);4-Hydroxyphenylacetic_acid_catabolic_pathway icw(3);4-Hydroxyphenylacetic_acid_catabolic_pathway.
 
 
 0.950
KIH83010.1
Icw(2);Aromatic_amino_acid_degradation icw(3);Aromatic_amino_acid_degradation icw(2);4-Hydroxyphenylacetic_acid_catabolic_pathway icw(3);4-Hydroxyphenylacetic_acid_catabolic_pathway.
 
 
 0.933
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.906
KIH83009.1
Transcriptional activator of 4-hydroxyphenylacetate 3-monooxygenase operon, XylS/AraC family; Icw(6);4- Hydroxyphenylacetic_acid_catabolic_pathway.
 
 
  0.897
KIH83409.1
Epoxide hydrolase; Isu;CBSS-410289.13.peg.3174.
  
 
 0.894
KIH83006.1
Fumarylacetoacetate hydrolase family protein; Idu(2);Gentisate_degradation idu(2);Pterin_carbinolamine_dehydratase idu(2);Salicylate_and_gentisate_catabolism.
 
 
 0.874
KIH83015.1
4-hydroxyphenylacetate symporter, major facilitator superfamily (MFS); Icw(6);4- Hydroxyphenylacetic_acid_catabolic_pathway.
  
    0.840
Your Current Organism:
Pseudomonas batumici
NCBI taxonomy Id: 226910
Other names: P. batumici, strain UCM B-321
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