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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
KIH81550.1Phosphomethylpyrimidine kinase; Isu;5-FCL-like_protein isu;Thiamin_biosynthesis. (265 aa)    
Predicted Functional Partners:
thiC
Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
 
 0.999
thiE
Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.992
KIH80859.1
Sulfur carrier protein ThiS; Icw(1);Thiamin_biosynthesis.
 
 
 0.975
KIH81999.1
Idu(1);Nudix_proteins_(nucleoside_triphosphate_hydr o lases) idu(1);Nudix_proteins_(nucleoside_triphosphate_hydrolases).
 
 
 0.955
KIH82025.1
Idu(1);Nudix_proteins_(nucleoside_triphosphate_hydr o lases) idu(1);Nudix_proteins_(nucleoside_triphosphate_hydrolases).
 
 
 0.955
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
    
 0.857
KIH85284.1
Molybdopterin biosynthesis protein MoeB; Isu;Molybdenum_cofactor_biosynthesis.
 
  
 0.844
hemL
Glutamate-1-semialdehyde aminotransferase; Isu;CBSS-196164.1.peg.461 isu;Heme_and_Siroheme_Biosynthesis.
  
  
 0.808
pdxY
Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.
   
 
 0.791
Your Current Organism:
Pseudomonas batumici
NCBI taxonomy Id: 226910
Other names: P. batumici, strain UCM B-321
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