STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
SDE43899.1
Succinate dehydrogenase subunit A.
 
 0.974
SDE43877.1
Succinate dehydrogenase / fumarate reductase iron-sulfur subunit.
 
 0.972
SDE53212.1
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.971
SDE31441.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.965
SDE33197.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.962
SDE35185.1
Glutamate synthase (ferredoxin).
   
 
 0.939
SDE55249.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 
 0.931
SDE85864.1
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase).
 
 0.913
SDF16389.1
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase).
 
 0.913
Your Current Organism:
Ulvibacter litoralis
NCBI taxonomy Id: 227084
Other names: Bacteroidetes bacterium KMM 3912, CCUG 47093, DSM 16195, DSM 19843, KCTC 12104, KMM 3912, U. litoralis, Ulvibacter litoralis Nedashkovskaya et al. 2004
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