STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCL44442.1Bifunctional non-homologous end joining protein LigD. (303 aa)    
Predicted Functional Partners:
SCL44440.1
Bifunctional non-homologous end joining protein LigD; Manually curated.
  
 0.999
SCL45776.1
Bifunctional non-homologous end joining protein LigD.
  
 0.997
SCL47860.1
ATP-dependent DNA ligase.
  
 0.957
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.947
ku-2
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.887
SCL64973.1
DNA ligase D.
  
  
 
0.774
lig
DNA ligase-1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
  
 0.765
SCL52312.1
DNA ligase D, polymerase domain-containing protein; Manually curated.
 
  
 
0.685
SCL47800.1
DNA ligase D.
 
  
 
0.678
SCL44444.1
NTE family protein.
       0.584
Your Current Organism:
Micromonospora eburnea
NCBI taxonomy Id: 227316
Other names: DSM 44814, JCM 12345, M. eburnea, Micromonospora eburnea Thawai et al. 2005, Micromonospora sp. LK2-10, Micromonospora sp. LK2-5, Micromonospora sp. LK210, NBRC 101912, PCU 238, PCU:238, strain LK2-10
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