STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (312 aa)    
Predicted Functional Partners:
SCL64855.1
Homoserine dehydrogenase.
 
 0.996
SCL64849.1
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.988
SCL67104.1
L-threonine synthase.
 
 
 0.983
SCL45774.1
Threonine synthase.
  
 
 0.980
SCL67682.1
Aspartate kinase; Belongs to the aspartokinase family.
  
 0.972
SCL58846.1
Threonine synthase.
 
 
 0.963
SCL51821.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.945
SCL46288.1
Branched-chain amino acid aminotransferase.
  
 
 0.908
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
    
 0.906
SCL44508.1
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.905
Your Current Organism:
Micromonospora eburnea
NCBI taxonomy Id: 227316
Other names: DSM 44814, JCM 12345, M. eburnea, Micromonospora eburnea Thawai et al. 2005, Micromonospora sp. LK2-10, Micromonospora sp. LK2-5, Micromonospora sp. LK210, NBRC 101912, PCU 238, PCU:238, strain LK2-10
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