STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANIA_06044Protein kinase NPKA. (467 aa)    
Predicted Functional Partners:
ANIA_04563
Casein kinase I (Eurofung); Belongs to the protein kinase superfamily.
  
  
0.692
ANIA_07719
Cyclin, putative (AFU_orthologue AFUA_5G08160).
   
 
 0.688
ssn8
RNA polymerase II holoenzyme cyclin-like subunit; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By s [...]
     
 0.670
nimA
G2-specific protein kinase nimA; Protein kinase that plays an important role in mitotic regulation. Seems to be phosphorylated and thereby activated by CDC2/cyclin B during mitotic activation. It is also required for spindle formation and for nuclear envelope breakdown.
  
  
 
0.658
plkA
Serine/threonine-protein kinase.
  
  
 
0.628
nudE
Nuclear distribution protein nudE; Required for nuclear migration within hyphae during vegetative growth; Belongs to the nudE family.
     
 0.579
ANIA_00699
Cell division protein kinase (Ctk1), putative (AFU_orthologue AFUA_1G13600).
  
 
0.480
ANIA_08261
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
  
 
0.476
ANIA_05618
Spindle pole body protein An-Cdc31 (Eurofung).
     
 0.474
ANIA_06914
EF-hand superfamily Ca2+-modulated protein (AFU_orthologue AFUA_5G13630).
     
 0.474
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.