STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANIA_10484DUF455 domain protein (AFU_orthologue AFUA_6G08690). (383 aa)    
Predicted Functional Partners:
cwc2
Pre-mRNA-splicing factor cwc2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]
    
  0.963
ANIA_06906
Cell cycle control protein (Cwf8), putative (AFU_orthologue AFUA_5G13510).
    
   0.958
ANIA_05196
mRNA splicing factor (Prp17), putative (AFU_orthologue AFUA_6G07300).
    
   0.950
cef1
Pre-mRNA-splicing factor cef1; Involved in pre-mRNA splicing and cell cycle control.
    
   0.946
ANIA_01408
Hypothetical U5 snRNP component (Eurofung).
    
   0.946
syf2
Pre-mRNA-splicing factor syf2; Involved in pre-mRNA splicing.
    
 0.617
ANIA_03739
RNP domain protein (AFU_orthologue AFUA_6G12300).
    
  0.591
ANIA_00282
RNA binding protein (AFU_orthologue AFUA_1G02950).
    
  0.591
syf1
Pre-mRNA-splicing factor syf1; Involved in pre-mRNA splicing and cell cycle progression.
   
 0.573
ANIA_05535
Cell cycle control protein (Cwf19), putative (AFU_orthologue AFUA_4G11830).
   
  0.562
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.