STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANIA_04591Phosphoglucomutase, putative (AFU_orthologue AFUA_2G02120). (614 aa)    
Predicted Functional Partners:
pgmB
Phosphoglucomutase; Catalyzes the reversible interconversion of glucose 1- phosphate and glucose 6-phosphate. Key enzyme in hexose metabolism. The reverse reaction is an essential step for biosynthesis because glucose 1-phosphate is the starting point for the synthesis of UDP-glucose, which acts as a precursor for the synthesis of oligosaccharides and trehalose (By similarity). Belongs to the phosphohexose mutase family.
  
 0.987
ANIA_01015
Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.982
ANIA_06037
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.982
ANIA_02440
Ribose 5-phosphate isomerase A (AFU_orthologue AFUA_6G10610).
    
 0.947
ANIA_07995
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
 0.942
ANIA_02638
Phosphotransferase.
   
 
 0.938
hxkA
Hexokinase; Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D- fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6- phosphate.
   
 
 0.938
ANIA_04255
Phosphotransferase.
   
 
 0.938
ANIA_05907
Uncharacterized protein.
    
 0.934
ANIA_03169
Ribose-phosphate pyrophosphokinase (AFU_orthologue AFUA_3G13380).
  
 0.930
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.