STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
stcFProbable sterigmatocystin biosynthesis P450 monooxygenase stcF; May be involved in the hydroxylation of averantin to form 5'- hydroxyaverantin, oxidation of averufin to 1-hydroxyversicolorone and its oxidation to versiconal hemiacetal acetate. (483 aa)    
Predicted Functional Partners:
stcE
Putative sterigmatocystin biosynthesis ketoreductase stcE; May be involved in the dehydration of norsolorinic acid to form averantin; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.970
ANIA_07817
Uncharacterized protein.
   
 
 0.927
stcA
Putative sterigmatocystin biosynthesis polyketide synthase; Involved in the synthesis of the polyketide nucleus of sterigmatocystin from hexanoyl-CoA and seven malonates.
   
 0.737
stcW
Putative sterigmatocystin biosynthesis monooxygenase stcW; May be involved in the hydroxylation of averantin to form 5'- hydroxyaverantin, oxidation of averufin to 1-hydroxyversicolorone and its oxidation to versiconal hemiacetal acetate.
   
 
 0.627
ANIA_03272
Cytochrome P450 oxidoreductase, putative (Eurofung); Belongs to the cytochrome P450 family.
  
     0.507
ANIA_01748
Cytochrome P450, putative (Eurofung); Belongs to the cytochrome P450 family.
  
     0.506
stcS
Probable sterigmatocystin biosynthesis P450 monooxygenase stcS; Catalyzes the conversion of versicolorin A to demethylsterigmatocystin.
  
  
0.490
stcQ
Averufin oxidase A homolog; Involved in the conversion of averufin (AVF) to versiconal hemiacetal acetate (VHA); Belongs to the avfA family.
   
  
 0.474
ANIA_06321
Cytochrome P450, putative (Eurofung); Belongs to the cytochrome P450 family.
  
     0.459
stcV
Putative sterigmatocystin biosynthesis dehydrogenase stcV; May be involved in the dehydration of 5'-hydroxyaverantin to form averufin; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
   
  
 0.437
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
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