STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppm1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (382 aa)    
Predicted Functional Partners:
pphA
Serine/threonine-protein phosphatase PP2A catalytic subunit; Involved in hyphal morphogenesis; Belongs to the PPP phosphatase family. PP-2A subfamily.
   
 0.972
ppe1
Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunit (By similarity); Belongs to the AB hydrolase superfamily.
      
 0.968
ANIA_09437
RING zinc finger protein, putative (AFU_orthologue AFUA_1G13920).
 
      0.859
ANIA_01545
Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
 0.840
ANIA_04085
Protein phosphotase 2a 65kd regulatory sububit (AFU_orthologue AFUA_1G05610).
    
 0.824
ANIA_00103
Serine/threonine-protein phosphatase.
    
 0.764
ANIA_04713
Ser/Thr protein phosphatase family (AFU_orthologue AFUA_5G08620).
    
 0.745
rrd2
Serine/threonine-protein phosphatase 2A activator 2; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A- phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
    
 
 0.717
bimB
Separin; Required for nuclear division. Could function in the mitotic spindle.
      
 0.693
rrd1
Serine/threonine-protein phosphatase 2A activator 1; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A- phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
    
 
 0.677
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
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