node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANIA_01060 | ANIA_06554 | C8VTU6 | C8V0T7 | Histone demethylase (Eurofung). | Histone domain-containing protein. | 0.894 |
ANIA_01060 | hhtA | C8VTU6 | P23753 | Histone demethylase (Eurofung). | Histone H3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.894 |
ANIA_01060 | htaA | C8VTU6 | P08844 | Histone demethylase (Eurofung). | Histone H2A; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.692 |
ANIA_01060 | htbA | C8VTU6 | P23754 | Histone demethylase (Eurofung). | Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.833 |
ANIA_01060 | htz1 | C8VTU6 | Q5AUJ1 | Histone demethylase (Eurofung). | Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] | 0.970 |
ANIA_06554 | ANIA_01060 | C8V0T7 | C8VTU6 | Histone domain-containing protein. | Histone demethylase (Eurofung). | 0.894 |
ANIA_06554 | ANIA_08863 | C8V0T7 | C8V9B5 | Histone domain-containing protein. | Putative nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. | 0.490 |
ANIA_06554 | htaA | C8V0T7 | P08844 | Histone domain-containing protein. | Histone H2A; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.959 |
ANIA_06554 | htbA | C8V0T7 | P23754 | Histone domain-containing protein. | Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.982 |
ANIA_06554 | htz1 | C8V0T7 | Q5AUJ1 | Histone domain-containing protein. | Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] | 0.967 |
ANIA_06554 | rvb1 | C8V0T7 | Q5BBV9 | Histone domain-containing protein. | RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. | 0.855 |
ANIA_06554 | spt16 | C8V0T7 | Q5B2X8 | Histone domain-containing protein. | FACT complex subunit spt16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] | 0.895 |
ANIA_07475 | htz1 | Q5AW55 | Q5AUJ1 | Signal transducer, putative (AFU_orthologue AFUA_2G05620). | Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] | 0.975 |
ANIA_07475 | rvb1 | Q5AW55 | Q5BBV9 | Signal transducer, putative (AFU_orthologue AFUA_2G05620). | RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. | 0.975 |
ANIA_07475 | swr1 | Q5AW55 | Q5ARK3 | Signal transducer, putative (AFU_orthologue AFUA_2G05620). | Helicase swr1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. | 0.974 |
ANIA_08863 | ANIA_06554 | C8V9B5 | C8V0T7 | Putative nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. | Histone domain-containing protein. | 0.490 |
ANIA_08863 | hhtA | C8V9B5 | P23753 | Putative nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. | Histone H3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.490 |
ANIA_08863 | htaA | C8V9B5 | P08844 | Putative nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. | Histone H2A; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.956 |
ANIA_08863 | htbA | C8V9B5 | P23754 | Putative nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. | Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.886 |
ANIA_08863 | htz1 | C8V9B5 | Q5AUJ1 | Putative nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. | Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] | 0.983 |