STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANIA_06874Alpha-1,2-mannosyltransferase (Alg2), putative (AFU_orthologue AFUA_5G13210). (478 aa)    
Predicted Functional Partners:
ANIA_05346
Beta-1,4-mannosyltransferase (Alg1), putative (AFU_orthologue AFUA_6G14180).
    
 0.973
ANIA_05725
Alpha-1,2-mannosyltransferase (Alg11), putative (AFU_orthologue AFUA_1G06890).
   
 0.945
mus81
Crossover junction endonuclease mus81; Interacts with eme1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family.
   
 0.801
be1
1,4-alpha-glucan-branching enzyme; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
 0.723
pgmB
Phosphoglucomutase; Catalyzes the reversible interconversion of glucose 1- phosphate and glucose 6-phosphate. Key enzyme in hexose metabolism. The reverse reaction is an essential step for biosynthesis because glucose 1-phosphate is the starting point for the synthesis of UDP-glucose, which acts as a precursor for the synthesis of oligosaccharides and trehalose (By similarity). Belongs to the phosphohexose mutase family.
   
 0.626
ANIA_05888
UDP-N-acetyl-glucosamine-1-P transferase Alg7, putative (AFU_orthologue AFUA_2G11240).
  
 
 0.625
ANIA_10710
Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
   
 0.601
ANIA_10060
Glycogen debranching enzyme Gdb1, putative (AFU_orthologue AFUA_1G02140).
  
 0.587
ANIA_02425
Protein phosphatase regulatory subunit Gac1, putative (AFU_orthologue AFUA_2G13850).
   
 0.586
ANIA_06878
ERCC4 domain-containing protein.
 
      0.585
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.