STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
imeBSerine/threonine protein kinase ime2 homologue imeB (Eurofung). (781 aa)    
Predicted Functional Partners:
ANIA_10497
DNA helicase; Belongs to the MCM family.
    
   0.946
ANIA_02491
DNA helicase; Belongs to the MCM family.
    
 
 0.946
ANIA_10072
Origin recognition complex subunit Orc5, putative (AFU_orthologue AFUA_1G02500).
    
   0.946
ANIA_07994
DNA helicase; Belongs to the MCM family.
    
   0.946
ANIA_07723
Origin recognition complex subunit 2, putative (AFU_orthologue AFUA_5G08110).
    
   0.946
ANIA_06070
MCM domain-containing protein; Belongs to the MCM family.
    
   0.946
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
    
   0.946
ANIA_05892
Origin recognition complex subunit Orc4, putative (AFU_orthologue AFUA_2G11170).
    
   0.946
ANIA_05676
Cell division control protein; Belongs to the CDC6/cdc18 family.
    
 
 0.946
ANIA_01435
Origin recognition complex subunit 3, putative (AFU_orthologue AFUA_8G04240).
    
   0.946
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.