node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANIA_04764 | ANIA_05998 | C8VAQ8 | Q5B0D2 | Histone-lysine N-methyltransferase (Ash1), putative (AFU_orthologue AFUA_3G06480). | SET and MYND domain protein, putative (AFU_orthologue AFUA_2G10080). | 0.909 |
ANIA_04764 | ANIA_06554 | C8VAQ8 | C8V0T7 | Histone-lysine N-methyltransferase (Ash1), putative (AFU_orthologue AFUA_3G06480). | Histone domain-containing protein. | 0.708 |
ANIA_04764 | dot1 | C8VAQ8 | Q5BH89 | Histone-lysine N-methyltransferase (Ash1), putative (AFU_orthologue AFUA_3G06480). | Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone. | 0.938 |
ANIA_04764 | hhtA | C8VAQ8 | P23753 | Histone-lysine N-methyltransferase (Ash1), putative (AFU_orthologue AFUA_3G06480). | Histone H3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.776 |
ANIA_04764 | set1 | C8VAQ8 | Q5B0Y5 | Histone-lysine N-methyltransferase (Ash1), putative (AFU_orthologue AFUA_3G06480). | Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. Belongs to the class V-like SAM-binding methyltransferase superfamily. | 0.921 |
ANIA_04764 | set2 | C8VAQ8 | Q5ASA5 | Histone-lysine N-methyltransferase (Ash1), putative (AFU_orthologue AFUA_3G06480). | Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | 0.974 |
ANIA_04764 | set9 | C8VAQ8 | Q5AZY3 | Histone-lysine N-methyltransferase (Ash1), putative (AFU_orthologue AFUA_3G06480). | Histone-lysine N-methyltransferase set9; Histone methyltransferase that trimethylates 'Lys-20' of histone H4 to form H4K20me3. | 0.948 |
ANIA_05998 | ANIA_04764 | Q5B0D2 | C8VAQ8 | SET and MYND domain protein, putative (AFU_orthologue AFUA_2G10080). | Histone-lysine N-methyltransferase (Ash1), putative (AFU_orthologue AFUA_3G06480). | 0.909 |
ANIA_05998 | dot1 | Q5B0D2 | Q5BH89 | SET and MYND domain protein, putative (AFU_orthologue AFUA_2G10080). | Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone. | 0.923 |
ANIA_05998 | hhfA | Q5B0D2 | P23750 | SET and MYND domain protein, putative (AFU_orthologue AFUA_2G10080). | Histone H4.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.457 |
ANIA_05998 | set1 | Q5B0D2 | Q5B0Y5 | SET and MYND domain protein, putative (AFU_orthologue AFUA_2G10080). | Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. Belongs to the class V-like SAM-binding methyltransferase superfamily. | 0.951 |
ANIA_05998 | set2 | Q5B0D2 | Q5ASA5 | SET and MYND domain protein, putative (AFU_orthologue AFUA_2G10080). | Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | 0.924 |
ANIA_05998 | set9 | Q5B0D2 | Q5AZY3 | SET and MYND domain protein, putative (AFU_orthologue AFUA_2G10080). | Histone-lysine N-methyltransferase set9; Histone methyltransferase that trimethylates 'Lys-20' of histone H4 to form H4K20me3. | 0.909 |
ANIA_06554 | ANIA_04764 | C8V0T7 | C8VAQ8 | Histone domain-containing protein. | Histone-lysine N-methyltransferase (Ash1), putative (AFU_orthologue AFUA_3G06480). | 0.708 |
ANIA_06554 | ANIA_10501 | C8V0T7 | C8V5Q0 | Histone domain-containing protein. | annotation not available | 0.817 |
ANIA_06554 | dot1 | C8V0T7 | Q5BH89 | Histone domain-containing protein. | Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone. | 0.934 |
ANIA_06554 | hhfA | C8V0T7 | P23750 | Histone domain-containing protein. | Histone H4.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.913 |
ANIA_06554 | htaA | C8V0T7 | P08844 | Histone domain-containing protein. | Histone H2A; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.959 |
ANIA_06554 | set1 | C8V0T7 | Q5B0Y5 | Histone domain-containing protein. | Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. Belongs to the class V-like SAM-binding methyltransferase superfamily. | 0.939 |
ANIA_06554 | set2 | C8V0T7 | Q5ASA5 | Histone domain-containing protein. | Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | 0.956 |