CBU_0200 protein (Coxiella burnetii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CBU_0200

Aldose 1-epimerase family protein. (295 aa)

Predicted Functional Partners:

coaA

0.773

CBU_0197

0.528

CBU_0198

0.528

CBU_0608

0.500

CBU_1346

0.500

birA

0.496

dacB

0.449

xylB

0.435

Your Current Organism:

Coxiella burnetii

NCBI taxonomy Id: 227377
Other names: C. burnetii RSA 493, Coxiella burnetii RSA 493, Coxiella burnetii str. RSA 493

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBU_0197	CBU_0198	CBU_0197	CBU_0198	Hypothetical outer membrane protein.	Outer membrane protein.	0.999
CBU_0197	CBU_0200	CBU_0197	CBU_0200	Hypothetical outer membrane protein.	Aldose 1-epimerase family protein.	0.528
CBU_0197	coaA	CBU_0197	CBU_0199	Hypothetical outer membrane protein.	Pantothenate kinase.	0.528
CBU_0198	CBU_0197	CBU_0198	CBU_0197	Outer membrane protein.	Hypothetical outer membrane protein.	0.999
CBU_0198	CBU_0200	CBU_0198	CBU_0200	Outer membrane protein.	Aldose 1-epimerase family protein.	0.528
CBU_0198	coaA	CBU_0198	CBU_0199	Outer membrane protein.	Pantothenate kinase.	0.528
CBU_0200	CBU_0197	CBU_0200	CBU_0197	Aldose 1-epimerase family protein.	Hypothetical outer membrane protein.	0.528
CBU_0200	CBU_0198	CBU_0200	CBU_0198	Aldose 1-epimerase family protein.	Outer membrane protein.	0.528
CBU_0200	CBU_0608	CBU_0200	CBU_0608	Aldose 1-epimerase family protein.	Phosphomevalonate kinase.	0.500
CBU_0200	CBU_1346	CBU_0200	CBU_1346	Aldose 1-epimerase family protein.	Trehalase.	0.500
CBU_0200	birA	CBU_0200	CBU_1002	Aldose 1-epimerase family protein.	Biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	0.496
CBU_0200	coaA	CBU_0200	CBU_0199	Aldose 1-epimerase family protein.	Pantothenate kinase.	0.773
CBU_0200	dacB	CBU_0200	CBU_0009	Aldose 1-epimerase family protein.	D-alanyl-meso-diaminopimelate endopeptidase.	0.449
CBU_0200	xylB	CBU_0200	CBU_0346	Aldose 1-epimerase family protein.	Xylulose kinase.	0.435
CBU_0608	CBU_0200	CBU_0608	CBU_0200	Phosphomevalonate kinase.	Aldose 1-epimerase family protein.	0.500
CBU_1346	CBU_0200	CBU_1346	CBU_0200	Trehalase.	Aldose 1-epimerase family protein.	0.500
birA	CBU_0200	CBU_1002	CBU_0200	Biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	Aldose 1-epimerase family protein.	0.496
birA	coaA	CBU_1002	CBU_0199	Biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	Pantothenate kinase.	0.414
coaA	CBU_0197	CBU_0199	CBU_0197	Pantothenate kinase.	Hypothetical outer membrane protein.	0.528
coaA	CBU_0198	CBU_0199	CBU_0198	Pantothenate kinase.	Outer membrane protein.	0.528