thiS protein (Coxiella burnetii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

thiS

ThiS. (67 aa)

Predicted Functional Partners:

thiDE

0.998

thiG

0.996

thiC

0.984

CBU_0876

0.894

CBU_0331

0.882

CBU_0335

0.558

Your Current Organism:

Coxiella burnetii

NCBI taxonomy Id: 227377
Other names: C. burnetii RSA 493, Coxiella burnetii RSA 493, Coxiella burnetii str. RSA 493

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBU_0331	CBU_0335	CBU_0331	CBU_0335	Glycine oxidase.	Acid phosphatase.	0.558
CBU_0331	CBU_0876	CBU_0331	CBU_0876	Glycine oxidase.	Molybdopterin biosynthesis MoeB protein.	0.481
CBU_0331	thiC	CBU_0331	CBU_0330	Glycine oxidase.	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.849
CBU_0331	thiDE	CBU_0331	CBU_0334	Glycine oxidase.	Phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.973
CBU_0331	thiG	CBU_0331	CBU_0333	Glycine oxidase.	Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.997
CBU_0331	thiS	CBU_0331	CBU_0332	Glycine oxidase.	ThiS.	0.882
CBU_0335	CBU_0331	CBU_0335	CBU_0331	Acid phosphatase.	Glycine oxidase.	0.558
CBU_0335	thiC	CBU_0335	CBU_0330	Acid phosphatase.	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.558
CBU_0335	thiDE	CBU_0335	CBU_0334	Acid phosphatase.	Phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.558
CBU_0335	thiG	CBU_0335	CBU_0333	Acid phosphatase.	Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.558
CBU_0335	thiS	CBU_0335	CBU_0332	Acid phosphatase.	ThiS.	0.558
CBU_0876	CBU_0331	CBU_0876	CBU_0331	Molybdopterin biosynthesis MoeB protein.	Glycine oxidase.	0.481
CBU_0876	thiC	CBU_0876	CBU_0330	Molybdopterin biosynthesis MoeB protein.	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.888
CBU_0876	thiDE	CBU_0876	CBU_0334	Molybdopterin biosynthesis MoeB protein.	Phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.977
CBU_0876	thiG	CBU_0876	CBU_0333	Molybdopterin biosynthesis MoeB protein.	Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.979
CBU_0876	thiS	CBU_0876	CBU_0332	Molybdopterin biosynthesis MoeB protein.	ThiS.	0.894
thiC	CBU_0331	CBU_0330	CBU_0331	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Glycine oxidase.	0.849
thiC	CBU_0335	CBU_0330	CBU_0335	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Acid phosphatase.	0.558
thiC	CBU_0876	CBU_0330	CBU_0876	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Molybdopterin biosynthesis MoeB protein.	0.888
thiC	thiDE	CBU_0330	CBU_0334	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.999