Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBU_2006Two-component response regulator. (245 aa)    
Predicted Functional Partners:
rstB
Sensor protein.
 
 0.993
CBU_1761
Two component system histidine kinase.
 
 
 0.987
phoR
Phosphate regulon sensor protein.
 
 0.986
CBU_0789
Two component system histidine kinase.
 
 
 0.986
CBU_1084
Two component system histidine kinase.
 
 0.972
qseC
Sensor protein.
 
 
 0.913
CBU_0634
Two component system histidine kinase.
 
 0.904
gacS
Sensor protein.
 
 
 
 0.888
CBU_2004
ADP-heptose--LPS heptosyltransferase.
  
  
 0.777
gacA.1
Response regulator.
  
 
 
 0.716
Your Current Organism:
Coxiella burnetii
NCBI taxonomy Id: 227377
Other names: C. burnetii RSA 493, Coxiella burnetii RSA 493, Coxiella burnetii str. RSA 493
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