STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
omcBOmcB; In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane porin. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan. It is present but the disulfide bonds are reduced in reticulate bodies (RBs) (By similarity). (558 aa)    
Predicted Functional Partners:
omcA
OmcA; Similar to GB:X79980, and PID:510454; identified by sequence similarity; small cysteine-rich protein; small CRP.
     
 0.845
ompA
Major outer membrane protein, porin; In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the large cysteine-rich periplasmic protein. It has been described in publications as the Sarkosyl- insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan. Belongs to the chlamydial porin (CP) (TC 1.B.2) family.
      
 0.811
CCA_00181
DNA binding domain, excisionase family; Similar to SP:P94661, and SP:P94661; identified by sequence similarity; putative; Belongs to the EUO family.
      
 0.811
CCA_00913
Major outer membrane protein, putative; Similar to GB:D28770, PID:523232, PID:523234, and PID:2335043; identified by sequence similarity; putative.
      
 0.809
hctA
Histone H1-like protein HC1.
      
 0.802
htrA
Serine protease, HtrA/DegQ/DegS family; Similar to GB:D14982, GB:Z33123, SP:P43044, and PID:416242; identified by sequence similarity; putative; Belongs to the peptidase S1C family.
      
 0.797
srp
Srp; Similar to GB:M81087, SP:P41171, and PID:154675; identified by sequence similarity; putative sulfur-rich protein.
     
 0.787
dnaK
dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
      
 0.774
groES
10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
      
 0.771
hctB
Hc2 nucleoprotein; Similar to GB:Z33880, and PID:535939; identified by sequence similarity; putative.
  
   
 0.714
Your Current Organism:
Chlamydia caviae
NCBI taxonomy Id: 227941
Other names: C. caviae GPIC, Chlamydia caviae GPIC, Chlamydophila caviae GPIC, Chlamydophila caviae str. GPIC
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