STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaZDNA polymerase III, gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (446 aa)    
Predicted Functional Partners:
dnaE
DNA polymerase III, alpha subunit; Similar to GP:8979038; identified by sequence similarity; putative.
 
 0.992
CCA_00509
DNA polymerase III, tau subunit, putative; Identified by match to PFAM protein family HMM PF02504.
 
 
0.985
dnaN
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
 
 
 0.983
CCA_00413
Conserved hypothetical protein; Similar to GB:Z33880, and PID:535939; identified by sequence similarity; putative.
   
 0.981
dnaQ-2
DNA polymerase III, epsilon chain; Identified by match to TIGR protein family HMM TIGR01406.
   
 0.974
CCA_00330
Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.931
dnaQ-1
DNA polymerase III, epsilon chain; Identified by match to TIGR protein family HMM TIGR01406.
   
 0.930
ssb
Single-strand binding protein; Identified by match to PFAM protein family HMM PF03995.
    
 
 0.813
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 
 
 
 0.765
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
  
 0.627
Your Current Organism:
Chlamydia caviae
NCBI taxonomy Id: 227941
Other names: C. caviae GPIC, Chlamydia caviae GPIC, Chlamydophila caviae GPIC, Chlamydophila caviae str. GPIC
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.