STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucA2-oxoglutarate dehydrogenase, E1 component; Identified by match to PFAM protein family HMM PF02779. (908 aa)    
Predicted Functional Partners:
sucB
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Identified by match to PFAM protein family HMM PF03347.
 
 0.999
CCA_00218
2-oxo acid dehydrogenase; Similar to GB:U02462, and PID:407294; identified by sequence similarity; putative.
 0.998
CCA_00933
2-oxo acid dehydrogenase, E3 component, lipoamide dehydrogenase, putative; Identified by match to PFAM protein family HMM PF02737.
  
 0.993
pdhC
Pyruvate dehydrogenase, E2 component, dihydrolipoamide S-acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.939
sucD
succinyl-Coa synthetase, alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.932
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.927
sdhB
Succinate dehydrogenase, iron-sulfur protein; Similar to GP:8979163; identified by sequence similarity; putative.
  
 
 0.899
pdhA/pdhB
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta subunit; Identified by match to PFAM protein family HMM PF02745.
   
 0.894
sdhA
Succinate dehydrogenase, flavoprotein subunit; Similar to GB:X56071, PID:507063, and SP:P51603; identified by sequence similarity; putative.
  
 
 0.857
CCA_00969
Succinate dehydrogenase, cytochrome b558 subunit, putative; Similar to GB:X56071, PID:507063, and SP:P51603; identified by sequence similarity; putative.
  
  
 0.846
Your Current Organism:
Chlamydia caviae
NCBI taxonomy Id: 227941
Other names: C. caviae GPIC, Chlamydia caviae GPIC, Chlamydophila caviae GPIC, Chlamydophila caviae str. GPIC
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.