node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCA_00772 | murB | CCA_00772 | CCA_00773 | N utilization substance protein B, putative; Identified by match to PFAM protein family HMM PF01029. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.761 |
CCA_00860 | mraY | CCA_00860 | CCA_00868 | Conserved hypothetical protein; Similar to GB:X72832; identified by sequence similarity; putative. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.457 |
CCA_00860 | murB | CCA_00860 | CCA_00773 | Conserved hypothetical protein; Similar to GB:X72832; identified by sequence similarity; putative. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.679 |
CCA_00860 | murC/ddlA | CCA_00860 | CCA_00863 | Conserved hypothetical protein; Similar to GB:X72832; identified by sequence similarity; putative. | UDP-N-acetylmuramate--alanine ligase/D-alanine--D-alanine ligase; Similar to GB:L16784, SP:P33395, and PID:290384; identified by sequence similarity; putative; In the C-terminal section; belongs to the D-alanine--D- alanine ligase family. | 0.850 |
CCA_00860 | murD | CCA_00860 | CCA_00867 | Conserved hypothetical protein; Similar to GB:X72832; identified by sequence similarity; putative. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.846 |
CCA_00860 | murE | CCA_00860 | CCA_00376 | Conserved hypothetical protein; Similar to GB:X72832; identified by sequence similarity; putative. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.564 |
CCA_00860 | murF | CCA_00860 | CCA_00869 | Conserved hypothetical protein; Similar to GB:X72832; identified by sequence similarity; putative. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | 0.743 |
CCA_00860 | murG | CCA_00860 | CCA_00864 | Conserved hypothetical protein; Similar to GB:X72832; identified by sequence similarity; putative. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.850 |
mraY | CCA_00860 | CCA_00868 | CCA_00860 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Conserved hypothetical protein; Similar to GB:X72832; identified by sequence similarity; putative. | 0.457 |
mraY | murA | CCA_00868 | CCA_00171 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.739 |
mraY | murB | CCA_00868 | CCA_00773 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.784 |
mraY | murC/ddlA | CCA_00868 | CCA_00863 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramate--alanine ligase/D-alanine--D-alanine ligase; Similar to GB:L16784, SP:P33395, and PID:290384; identified by sequence similarity; putative; In the C-terminal section; belongs to the D-alanine--D- alanine ligase family. | 0.979 |
mraY | murD | CCA_00868 | CCA_00867 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.993 |
mraY | murE | CCA_00868 | CCA_00376 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.927 |
mraY | murF | CCA_00868 | CCA_00869 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | 0.998 |
mraY | murG | CCA_00868 | CCA_00864 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.998 |
murA | mraY | CCA_00171 | CCA_00868 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.739 |
murA | murB | CCA_00171 | CCA_00773 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.974 |
murA | murC/ddlA | CCA_00171 | CCA_00863 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylmuramate--alanine ligase/D-alanine--D-alanine ligase; Similar to GB:L16784, SP:P33395, and PID:290384; identified by sequence similarity; putative; In the C-terminal section; belongs to the D-alanine--D- alanine ligase family. | 0.823 |
murA | murD | CCA_00171 | CCA_00867 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.785 |