STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNOK_03094003-hydroxy-3-methylglutaryl coenzyme A reductase. (1327 aa)    
Predicted Functional Partners:
PNOK_0466500
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.992
PNOK_0517000
Family prenyltransferase.
   
 
 0.920
PNOK_0577700
Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.
  
 
 0.919
PNOK_0138100
Uncharacterized protein.
   
 
 0.917
PNOK_0548900
Synoviolin 1 isoform b.
   
 
 0.904
PNOK_0473700
Squalene epoxidase.
   
  
 0.830
PNOK_0473600
Squalene epoxidase.
   
  
 0.830
PNOK_0225400
CBS-domain-containing.
    
 0.829
PNOK_0760000
Ring finger domain-containing.
   
 
 0.789
PNOK_0300300
Helix-loop-helix dna-binding domain-containing.
     
 0.782
Your Current Organism:
Pyrrhoderma noxium
NCBI taxonomy Id: 2282107
Other names: Fomes noxius, P. noxium, Phellinidium noxium, Phellinus noxius, Pyrrhoderma noxium (Corner) L.W. Zhou & Y.C. Dai, 2018
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