| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RMCC_0345 | RMCC_2000 | RMCC_0345 | RMCC_2000 | Family 3 adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | 0.673 |
| RMCC_0345 | RMCC_3046 | RMCC_0345 | RMCC_3046 | Family 3 adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.726 |
| RMCC_0345 | gmk | RMCC_0345 | RMCC_1219 | Family 3 adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.433 |
| RMCC_0345 | ndk | RMCC_0345 | RMCC_3398 | Family 3 adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.832 |
| RMCC_0345 | ribBA | RMCC_0345 | RMCC_1194 | Family 3 adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.881 |
| RMCC_2000 | RMCC_0345 | RMCC_2000 | RMCC_0345 | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | Family 3 adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.673 |
| RMCC_2000 | RMCC_3046 | RMCC_2000 | RMCC_3046 | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.688 |
| RMCC_2000 | adk | RMCC_2000 | RMCC_4272 | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.643 |
| RMCC_2000 | gmk | RMCC_2000 | RMCC_1219 | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.629 |
| RMCC_2000 | msrA | RMCC_2000 | RMCC_6275 | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.729 |
| RMCC_2000 | ndk | RMCC_2000 | RMCC_3398 | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.634 |
| RMCC_2000 | nrdE | RMCC_2000 | RMCC_2002 | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.992 |
| RMCC_2000 | nrdF2 | RMCC_2000 | RMCC_2013 | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | Ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.887 |
| RMCC_2000 | nrdI | RMCC_2000 | RMCC_2001 | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | Ribonucleotide reductase stimulatory protein; Probably involved in ribonucleotide reductase function. | 0.988 |
| RMCC_2000 | ribBA | RMCC_2000 | RMCC_1194 | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.681 |
| RMCC_3046 | RMCC_0345 | RMCC_3046 | RMCC_0345 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Family 3 adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.726 |
| RMCC_3046 | RMCC_2000 | RMCC_3046 | RMCC_2000 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | 0.688 |
| RMCC_3046 | msrA | RMCC_3046 | RMCC_6275 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.638 |
| RMCC_3046 | nrdE | RMCC_3046 | RMCC_2002 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.621 |
| adk | RMCC_2000 | RMCC_4272 | RMCC_2000 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. | 0.643 |