STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (496 aa)    
Predicted Functional Partners:
RMCC_2987
Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family.
  
 0.996
cobD
Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 
 0.992
RMCC_2986
precorrin-8X methylmutase.
 
 0.991
RMCC_2247
cob(I)yrinic acid a,c-diamide adenosyltransferase.
 
  
 0.984
RMCC_2990
Precorrin-4 c11-methyltransferase cobM; Belongs to the precorrin methyltransferase family.
 
 
 0.977
RMCC_0260
Adenosyl cobinamide kinase.
 
 
 0.973
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.961
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.950
RMCC_2989
Cobalt-precorrin-6x reductase.
 
  
 0.943
RMCC_2991
Precorrin-6y methyltransferase cobL.
 
  
 0.943
Your Current Organism:
Mycolicibacterium canariasense
NCBI taxonomy Id: 228230
Other names: CCUG 47953, CIP 107998, DSM 44828, JCM 15298, M. canariasense, Mycobacterium canariasense, Mycobacterium canariasense Jimenez et al. 2004, Mycolicibacterium canariasense (Jimenez et al. 2004) Gupta et al. 2018, strain 502329
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