STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RMCC_2515L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family. (389 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
  0.899
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
  0.896
RMCC_2514
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
    
  0.691
RMCC_1124
methylmalonyl-CoA mutase.
    
 0.669
RMCC_1125
methylmalonyl-CoA mutase small subunit mutA.
    
 0.669
RMCC_4967
Short-chain type dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  0.610
RMCC_6708
3-hydroxyacyl-CoA dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  0.610
RMCC_3883
Oxidoreductase subunit alpha.
    
 0.602
RMCC_3990
HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.561
RMCC_2344
Acyl dehydratase.
 
  
  0.549
Your Current Organism:
Mycolicibacterium canariasense
NCBI taxonomy Id: 228230
Other names: CCUG 47953, CIP 107998, DSM 44828, JCM 15298, M. canariasense, Mycobacterium canariasense, Mycobacterium canariasense Jimenez et al. 2004, Mycolicibacterium canariasense (Jimenez et al. 2004) Gupta et al. 2018, strain 502329
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