node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RMCC_2107 | RMCC_3046 | RMCC_2107 | RMCC_3046 | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.972 |
RMCC_2107 | RMCC_3411 | RMCC_2107 | RMCC_3411 | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | Cysteine synthase. | 0.898 |
RMCC_2107 | RMCC_3840 | RMCC_2107 | RMCC_3840 | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | Lyase. | 0.964 |
RMCC_2107 | RMCC_4372 | RMCC_2107 | RMCC_4372 | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | Cystathionine gamma-synthase. | 0.903 |
RMCC_2107 | cysN | RMCC_2107 | RMCC_3719 | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.567 |
RMCC_2107 | metZ | RMCC_2107 | RMCC_4783 | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.913 |
RMCC_2107 | nirA_2 | RMCC_2107 | RMCC_1022 | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | Ferredoxin-dependent nitrite/sulfite reductase NirA; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.765 |
RMCC_3046 | RMCC_2107 | RMCC_3046 | RMCC_2107 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | 0.972 |
RMCC_3046 | RMCC_3411 | RMCC_3046 | RMCC_3411 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase. | 0.806 |
RMCC_3046 | RMCC_3412 | RMCC_3046 | RMCC_3412 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Transporter. | 0.436 |
RMCC_3046 | RMCC_3840 | RMCC_3046 | RMCC_3840 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Lyase. | 0.929 |
RMCC_3046 | RMCC_4372 | RMCC_3046 | RMCC_4372 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase. | 0.973 |
RMCC_3046 | cysN | RMCC_3046 | RMCC_3719 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.641 |
RMCC_3046 | metZ | RMCC_3046 | RMCC_4783 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.972 |
RMCC_3046 | nirA_2 | RMCC_3046 | RMCC_1022 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ferredoxin-dependent nitrite/sulfite reductase NirA; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.424 |
RMCC_3046 | serC | RMCC_3046 | RMCC_3509 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.416 |
RMCC_3410 | RMCC_3411 | RMCC_3410 | RMCC_3411 | Uncharacterized protein. | Cysteine synthase. | 0.911 |
RMCC_3410 | RMCC_3412 | RMCC_3410 | RMCC_3412 | Uncharacterized protein. | Transporter. | 0.893 |
RMCC_3411 | RMCC_2107 | RMCC_3411 | RMCC_2107 | Cysteine synthase. | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | 0.898 |
RMCC_3411 | RMCC_3046 | RMCC_3411 | RMCC_3046 | Cysteine synthase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.806 |