STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoE-2RNA polymerase sigma-E factor; Belongs to the sigma-70 factor family. ECF subfamily. (222 aa)    
Predicted Functional Partners:
rpoC-2
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.897
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.897
RMCC_0036
Anti-sigma factor.
  
 
 0.803
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.775
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.775
RMCC_4270
RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.760
RMCC_5103
ECF subfamily RNA polymerase sigma-24 factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.736
RMCC_6129
RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.736
RMCC_3271
Alternative RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.731
RMCC_3277
RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.722
Your Current Organism:
Mycolicibacterium canariasense
NCBI taxonomy Id: 228230
Other names: CCUG 47953, CIP 107998, DSM 44828, JCM 15298, M. canariasense, Mycobacterium canariasense, Mycobacterium canariasense Jimenez et al. 2004, Mycolicibacterium canariasense (Jimenez et al. 2004) Gupta et al. 2018, strain 502329
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.