STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceEPyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (929 aa)    
Predicted Functional Partners:
RMCC_0948
Catalytic domain of components of various dehydr ogenase complexes.
 
 0.987
RMCC_3987
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component.
  
 0.979
sucB
2-oxoglutarate dehydrogenase E2 component.
 
 0.961
RMCC_5225
Dihydrolipoamide acyltransferase.
 
 0.960
RMCC_5389
Alpha-ketoglutarate decarboxylase.
 
 0.959
RMCC_4664
Dihydrolipoamide dehydrogenase.
  
 
 0.953
RMCC_3640
2-oxoglutarate dehydrogenase, E1 component.
  
 0.947
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
     
 0.922
RMCC_3883
Oxidoreductase subunit alpha.
     
 0.913
RMCC_3989
Pyruvate dehydrogenase E1 component alpha subunit pdhA.
    
 0.912
Your Current Organism:
Mycolicibacterium canariasense
NCBI taxonomy Id: 228230
Other names: CCUG 47953, CIP 107998, DSM 44828, JCM 15298, M. canariasense, Mycobacterium canariasense, Mycobacterium canariasense Jimenez et al. 2004, Mycolicibacterium canariasense (Jimenez et al. 2004) Gupta et al. 2018, strain 502329
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.