STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RMCC_4378acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)    
Predicted Functional Partners:
RMCC_1288
3-hydroxyacyl-CoA dehydrogenase.
 
 0.996
RMCC_4655
3-hydroxybutyryl-CoA dehydrogenase.
 0.987
RMCC_4846
3-hydroxybutyryl-CoA dehydrogenase.
 
 0.964
RMCC_5575
acetyl-CoA acetyltransferase.
  
 0.942
RMCC_2344
Acyl dehydratase.
  
 0.936
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.925
RMCC_3499
Type II citrate synthase; Belongs to the citrate synthase family.
   
 0.912
RMCC_3503
Citrate synthase 2; Belongs to the citrate synthase family.
   
 0.912
RMCC_1644
acetoacetyl-CoA synthetase.
  
 
  0.911
RMCC_5680
acetyl-CoA synthetase.
  
 
 0.911
Your Current Organism:
Mycolicibacterium canariasense
NCBI taxonomy Id: 228230
Other names: CCUG 47953, CIP 107998, DSM 44828, JCM 15298, M. canariasense, Mycobacterium canariasense, Mycobacterium canariasense Jimenez et al. 2004, Mycolicibacterium canariasense (Jimenez et al. 2004) Gupta et al. 2018, strain 502329
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.