Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RMCC_4972Type 12 methyltransferase. (209 aa)    
Predicted Functional Partners:
RMCC_4971
TetR family transcriptional regulator.
   
   0.831
RMCC_6372
Polyketide synthase pks13.
    
 0.695
RMCC_4970
MMPL domain-containing protein.
       0.684
cysN
Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
 
 0.662
pks5-2
Polyketide synthase pks5.
   
 0.629
RMCC_6601
Beta-ketoacyl synthase.
   
 0.629
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.628
RMCC_1013
Polyketide synthetase mbtD.
   
 0.606
RMCC_3640
2-oxoglutarate dehydrogenase, E1 component.
     
  0.586
RMCC_5389
Alpha-ketoglutarate decarboxylase.
     
  0.586
Your Current Organism:
Mycolicibacterium canariasense
NCBI taxonomy Id: 228230
Other names: CCUG 47953, CIP 107998, DSM 44828, JCM 15298, M. canariasense, Mycobacterium canariasense, Mycobacterium canariasense Jimenez et al. 2004, Mycolicibacterium canariasense (Jimenez et al. 2004) Gupta et al. 2018, strain 502329
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