node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RMCC_0255 | RMCC_2082 | RMCC_0255 | RMCC_2082 | Branched-chain amino acid aminotransferase. | Acetolactate synthase 1 catalytic subunit. | 0.746 |
RMCC_0255 | RMCC_4778 | RMCC_0255 | RMCC_4778 | Branched-chain amino acid aminotransferase. | Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.886 |
RMCC_0255 | ilvC | RMCC_0255 | RMCC_2084 | Branched-chain amino acid aminotransferase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.886 |
RMCC_0255 | ilvD-2 | RMCC_0255 | RMCC_6694 | Branched-chain amino acid aminotransferase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.981 |
RMCC_0255 | ilvH | RMCC_0255 | RMCC_2083 | Branched-chain amino acid aminotransferase. | Acetolactate synthase 3 regulatory subunit. | 0.812 |
RMCC_0255 | leuA | RMCC_0255 | RMCC_6495 | Branched-chain amino acid aminotransferase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.985 |
RMCC_0255 | leuB | RMCC_0255 | RMCC_2088 | Branched-chain amino acid aminotransferase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.725 |
RMCC_0255 | leuC | RMCC_0255 | RMCC_2100 | Branched-chain amino acid aminotransferase. | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.709 |
RMCC_0255 | leuD | RMCC_0255 | RMCC_2101 | Branched-chain amino acid aminotransferase. | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.493 |
RMCC_0255 | panB | RMCC_0255 | RMCC_0231 | Branched-chain amino acid aminotransferase. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.905 |
RMCC_2082 | RMCC_0255 | RMCC_2082 | RMCC_0255 | Acetolactate synthase 1 catalytic subunit. | Branched-chain amino acid aminotransferase. | 0.746 |
RMCC_2082 | RMCC_4778 | RMCC_2082 | RMCC_4778 | Acetolactate synthase 1 catalytic subunit. | Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.652 |
RMCC_2082 | ilvC | RMCC_2082 | RMCC_2084 | Acetolactate synthase 1 catalytic subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
RMCC_2082 | ilvD-2 | RMCC_2082 | RMCC_6694 | Acetolactate synthase 1 catalytic subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.923 |
RMCC_2082 | ilvH | RMCC_2082 | RMCC_2083 | Acetolactate synthase 1 catalytic subunit. | Acetolactate synthase 3 regulatory subunit. | 0.999 |
RMCC_2082 | leuA | RMCC_2082 | RMCC_6495 | Acetolactate synthase 1 catalytic subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.985 |
RMCC_2082 | leuB | RMCC_2082 | RMCC_2088 | Acetolactate synthase 1 catalytic subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.975 |
RMCC_2082 | leuC | RMCC_2082 | RMCC_2100 | Acetolactate synthase 1 catalytic subunit. | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.865 |
RMCC_2082 | leuD | RMCC_2082 | RMCC_2101 | Acetolactate synthase 1 catalytic subunit. | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.876 |
RMCC_4778 | RMCC_0255 | RMCC_4778 | RMCC_0255 | Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | Branched-chain amino acid aminotransferase. | 0.886 |