node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RMCC_3883 | RMCC_6735 | RMCC_3883 | RMCC_6735 | Oxidoreductase subunit alpha. | D-isomer specific 2-hydroxyacid dehydrogenase. | 0.679 |
RMCC_3883 | gcvP | RMCC_3883 | RMCC_2808 | Oxidoreductase subunit alpha. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.447 |
RMCC_3883 | rplF | RMCC_3883 | RMCC_4292 | Oxidoreductase subunit alpha. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.516 |
RMCC_6735 | RMCC_3883 | RMCC_6735 | RMCC_3883 | D-isomer specific 2-hydroxyacid dehydrogenase. | Oxidoreductase subunit alpha. | 0.679 |
RMCC_6735 | gcvP | RMCC_6735 | RMCC_2808 | D-isomer specific 2-hydroxyacid dehydrogenase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.732 |
RMCC_6735 | rplB | RMCC_6735 | RMCC_4320 | D-isomer specific 2-hydroxyacid dehydrogenase. | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.673 |
RMCC_6735 | rplF | RMCC_6735 | RMCC_4292 | D-isomer specific 2-hydroxyacid dehydrogenase. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.683 |
RMCC_6735 | rplM | RMCC_6735 | RMCC_6222 | D-isomer specific 2-hydroxyacid dehydrogenase. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.671 |
RMCC_6735 | rplP | RMCC_6735 | RMCC_4316 | D-isomer specific 2-hydroxyacid dehydrogenase. | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.707 |
RMCC_6735 | rplU | RMCC_6735 | RMCC_3396 | D-isomer specific 2-hydroxyacid dehydrogenase. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.671 |
RMCC_6735 | rplV | RMCC_6735 | RMCC_4318 | D-isomer specific 2-hydroxyacid dehydrogenase. | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. | 0.681 |
RMCC_6735 | rpmA | RMCC_6735 | RMCC_3395 | D-isomer specific 2-hydroxyacid dehydrogenase. | 50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.671 |
RMCC_6735 | serC | RMCC_6735 | RMCC_3509 | D-isomer specific 2-hydroxyacid dehydrogenase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.905 |
gcvP | RMCC_3883 | RMCC_2808 | RMCC_3883 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Oxidoreductase subunit alpha. | 0.447 |
gcvP | RMCC_6735 | RMCC_2808 | RMCC_6735 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | D-isomer specific 2-hydroxyacid dehydrogenase. | 0.732 |
gcvP | rplB | RMCC_2808 | RMCC_4320 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.710 |
gcvP | serC | RMCC_2808 | RMCC_3509 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.421 |
rplB | RMCC_6735 | RMCC_4320 | RMCC_6735 | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | D-isomer specific 2-hydroxyacid dehydrogenase. | 0.673 |
rplB | gcvP | RMCC_4320 | RMCC_2808 | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.710 |
rplB | rplF | RMCC_4320 | RMCC_4292 | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.999 |