STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSM_0435Inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: hso:HS_1576 dehydrogenase. (336 aa)    
Predicted Functional Partners:
iolE
Xylose isomerase domain protein TIM barrel; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). Belongs to the IolE/MocC family.
 
 
 0.998
HSM_0433
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: hso:HS_1578 myo-inositol catabolism protein; Belongs to the TPP enzyme family.
 
  
 0.966
HSM_0424
PFAM: Myo-inositol catabolism IolB domain protein; KEGG: hso:HS_1587 conserved hypothetical protein.
 
  
 0.929
HSM_0151
PFAM: inositol monophosphatase; KEGG: hso:HS_0278 inositol-1(or 4)-monophosphatase.
    
 0.911
HSM_0175
PFAM: PfkB domain protein; KEGG: hso:HS_0303 myo-inositol catabolism protein.
 
  
 0.860
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
  
 
 0.694
lysS
TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: hso:HS_1477 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.605
HSM_1118
TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: hso:HS_0707 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.525
HSM_0427
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: hso:HS_1584 NAD-dependent aldehyde dehydrogenase.
 
  
 0.477
HSM_0727
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: hso:HS_0402 sensor histidine kinase.
    
 0.431
Your Current Organism:
Histophilus somni
NCBI taxonomy Id: 228400
Other names: H. somni 2336, Haemophilus somnus 2336, Histophilus somni 2336, Histophilus somni str. 2336
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