STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (320 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.998
bioA
Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by similarity to SP:P12995; match to protein family HMM PF00202; match to protein family HMM TIGR00508; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.997
HNE_1759
biotin--acetyl-CoA-carboxylase ligase; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121.
  
 
 0.944
bioF
8-amino-7-oxononanoate synthase; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212.
  
 0.811
argD
Acetylornithine/succinylornithine aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.786
HNE_1590
Putative serine C-palmitoyltransferase; Identified by similarity to GB:BAB56013.1; match to protein family HMM PF00155; match to protein family HMM PF00202; match to protein family HMM PF00464; match to protein family HMM PF01053; match to protein family HMM PF01212.
 
  
 0.728
leuC1
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
    
 0.706
hemA
5-aminolevulinic acid synthase; Identified by similarity to SP:Q04512; match to protein family HMM PF00155; match to protein family HMM TIGR01821.
 
  
 0.706
cysK
Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.
     
 0.563
kefC
Glutathione-regulated potassium-efflux system protein KefC; Identified by similarity to SP:P03819; match to protein family HMM PF00999; match to protein family HMM PF02254; match to protein family HMM TIGR00932; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
    0.523
Your Current Organism:
Hyphomonas neptunium
NCBI taxonomy Id: 228405
Other names: H. neptunium ATCC 15444, Hyphomonas neptunium ATCC 15444, Hyphomonas neptunium str. ATCC 15444, Hyphomonas neptunium strain ATCC 15444
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.