node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HNE_0530 | HNE_0533 | HNE_0530 | HNE_0533 | TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715. | Putative 6-pyruvoyl tetrahydropterin synthase; Identified by match to protein family HMM PF01242. | 0.470 |
HNE_0530 | exsB | HNE_0530 | HNE_0531 | TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.470 |
HNE_0530 | queE | HNE_0530 | HNE_0532 | TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.470 |
HNE_0533 | HNE_0530 | HNE_0533 | HNE_0530 | Putative 6-pyruvoyl tetrahydropterin synthase; Identified by match to protein family HMM PF01242. | TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715. | 0.470 |
HNE_0533 | HNE_0534 | HNE_0533 | HNE_0534 | Putative 6-pyruvoyl tetrahydropterin synthase; Identified by match to protein family HMM PF01242. | Transporter, small conductance mechanosensitive ion channel (MscS) family; Identified by match to protein family HMM PF00924. | 0.590 |
HNE_0533 | HNE_2538 | HNE_0533 | HNE_2538 | Putative 6-pyruvoyl tetrahydropterin synthase; Identified by match to protein family HMM PF01242. | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.779 |
HNE_0533 | exsB | HNE_0533 | HNE_0531 | Putative 6-pyruvoyl tetrahydropterin synthase; Identified by match to protein family HMM PF01242. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.981 |
HNE_0533 | folE1 | HNE_0533 | HNE_1855 | Putative 6-pyruvoyl tetrahydropterin synthase; Identified by match to protein family HMM PF01242. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.938 |
HNE_0533 | folE2 | HNE_0533 | HNE_3203 | Putative 6-pyruvoyl tetrahydropterin synthase; Identified by match to protein family HMM PF01242. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.983 |
HNE_0533 | queA | HNE_0533 | HNE_2757 | Putative 6-pyruvoyl tetrahydropterin synthase; Identified by match to protein family HMM PF01242. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.402 |
HNE_0533 | queE | HNE_0533 | HNE_0532 | Putative 6-pyruvoyl tetrahydropterin synthase; Identified by match to protein family HMM PF01242. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
HNE_0534 | HNE_0533 | HNE_0534 | HNE_0533 | Transporter, small conductance mechanosensitive ion channel (MscS) family; Identified by match to protein family HMM PF00924. | Putative 6-pyruvoyl tetrahydropterin synthase; Identified by match to protein family HMM PF01242. | 0.590 |
HNE_0534 | exsB | HNE_0534 | HNE_0531 | Transporter, small conductance mechanosensitive ion channel (MscS) family; Identified by match to protein family HMM PF00924. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.595 |
HNE_0534 | queE | HNE_0534 | HNE_0532 | Transporter, small conductance mechanosensitive ion channel (MscS) family; Identified by match to protein family HMM PF00924. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.590 |
HNE_2538 | HNE_0533 | HNE_2538 | HNE_0533 | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative 6-pyruvoyl tetrahydropterin synthase; Identified by match to protein family HMM PF01242. | 0.779 |
HNE_2538 | exsB | HNE_2538 | HNE_0531 | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.912 |
HNE_2538 | folE1 | HNE_2538 | HNE_1855 | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.978 |
HNE_2538 | queE | HNE_2538 | HNE_0532 | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.966 |
HNE_2538 | ribAB | HNE_2538 | HNE_2056 | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.442 |
exsB | HNE_0530 | HNE_0531 | HNE_0530 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715. | 0.470 |