Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HNE_0809Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028. (446 aa)    
Predicted Functional Partners:
HNE_0672
Enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737.
  
 0.981
HNE_0984
Conserved hypothetical protein; Identified by similarity to GB:AAS03215.1.
 
  0.952
HNE_2706
Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.948
HNE_3133
Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.948
HNE_0566
enoyl-CoA hydratase; Identified by similarity to SP:P14604; match to protein family HMM PF00378.
  
  0.945
HNE_1277
Carboxyl transferase domain protein; Identified by match to protein family HMM PF01039.
  
 
 0.932
mccA
methylcrotonoyl-CoA carboxylase alpha chain; Identified by similarity to SP:Q42523; match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786.
  
 0.915
HNE_0930
Identified by match to protein family HMM PF01636.
 
   0.870
HNE_0671
Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.820
HNE_0758
Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.820
Your Current Organism:
Hyphomonas neptunium
NCBI taxonomy Id: 228405
Other names: H. neptunium ATCC 15444, Hyphomonas neptunium ATCC 15444, Hyphomonas neptunium str. ATCC 15444, Hyphomonas neptunium strain ATCC 15444
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