STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (150 aa)    
Predicted Functional Partners:
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
 
  
 0.945
rnhB
Ribonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
 
 0.798
HNE_0812
Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.
 
    
 0.769
ssb
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
 
 0.766
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.726
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 
 0.670
HNE_0946
Putative lipoprotein.
       0.636
HNE_2532
ATP-dependent DNA helicase, RecQ family/ UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.
  
 
 0.573
thrB
Homoserine kinase; Identified by similarity to SP:P29364; match to protein family HMM PF01636; match to protein family HMM TIGR00938; Belongs to the pseudomonas-type ThrB family.
       0.568
HNE_1508
Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518.
  
 
 0.559
Your Current Organism:
Hyphomonas neptunium
NCBI taxonomy Id: 228405
Other names: H. neptunium ATCC 15444, Hyphomonas neptunium ATCC 15444, Hyphomonas neptunium str. ATCC 15444, Hyphomonas neptunium strain ATCC 15444
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.