node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HNE_0672 | HNE_1401 | HNE_0672 | HNE_1401 | Enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | Transporter, solute:sodium symporter (SSS) family; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.411 |
HNE_0672 | acsA | HNE_0672 | HNE_1402 | Enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.969 |
HNE_0672 | maeB | HNE_0672 | HNE_0296 | Enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | NADP-dependent malic enzyme; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | 0.654 |
HNE_1024 | HNE_1401 | HNE_1024 | HNE_1401 | Sugar isomerase, KpsF/GutQ family; Identified by match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily. | Transporter, solute:sodium symporter (SSS) family; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.442 |
HNE_1024 | maeB | HNE_1024 | HNE_0296 | Sugar isomerase, KpsF/GutQ family; Identified by match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily. | NADP-dependent malic enzyme; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | 0.420 |
HNE_1399 | HNE_1400 | HNE_1399 | HNE_1400 | Identified by match to protein family HMM PF04909. | Conserved hypothetical protein. | 0.494 |
HNE_1399 | HNE_1401 | HNE_1399 | HNE_1401 | Identified by match to protein family HMM PF04909. | Transporter, solute:sodium symporter (SSS) family; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.488 |
HNE_1400 | HNE_1399 | HNE_1400 | HNE_1399 | Conserved hypothetical protein. | Identified by match to protein family HMM PF04909. | 0.494 |
HNE_1400 | HNE_1401 | HNE_1400 | HNE_1401 | Conserved hypothetical protein. | Transporter, solute:sodium symporter (SSS) family; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.969 |
HNE_1400 | acsA | HNE_1400 | HNE_1402 | Conserved hypothetical protein. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.583 |
HNE_1401 | HNE_0672 | HNE_1401 | HNE_0672 | Transporter, solute:sodium symporter (SSS) family; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | 0.411 |
HNE_1401 | HNE_1024 | HNE_1401 | HNE_1024 | Transporter, solute:sodium symporter (SSS) family; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Sugar isomerase, KpsF/GutQ family; Identified by match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.442 |
HNE_1401 | HNE_1399 | HNE_1401 | HNE_1399 | Transporter, solute:sodium symporter (SSS) family; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Identified by match to protein family HMM PF04909. | 0.488 |
HNE_1401 | HNE_1400 | HNE_1401 | HNE_1400 | Transporter, solute:sodium symporter (SSS) family; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Conserved hypothetical protein. | 0.969 |
HNE_1401 | acsA | HNE_1401 | HNE_1402 | Transporter, solute:sodium symporter (SSS) family; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.917 |
HNE_1401 | maeB | HNE_1401 | HNE_0296 | Transporter, solute:sodium symporter (SSS) family; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | NADP-dependent malic enzyme; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | 0.473 |
acsA | HNE_0672 | HNE_1402 | HNE_0672 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | 0.969 |
acsA | HNE_1400 | HNE_1402 | HNE_1400 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Conserved hypothetical protein. | 0.583 |
acsA | HNE_1401 | HNE_1402 | HNE_1401 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Transporter, solute:sodium symporter (SSS) family; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.917 |
acsA | maeB | HNE_1402 | HNE_0296 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | NADP-dependent malic enzyme; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | 0.705 |