STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysESerine O-acetyltransferase; Identified by similarity to SP:P05796; match to protein family HMM PF00132; match to protein family HMM PF06426; match to protein family HMM TIGR01172. (269 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.
 
 0.992
HNE_0181
Cysteine synthase/cystathionine beta-synthase family protein; Identified by similarity to SP:P37887; match to protein family HMM PF00291.
 
 0.991
HNE_1420
Cysteine synthase/cystathionine beta-synthase family protein; Identified by similarity to SP:P50867; match to protein family HMM PF00291.
 
 0.986
cysS
cysteinyl-tRNA synthetase; Identified by match to protein family HMM PF01406; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.985
sdaA
L-serine ammonia-lyase; Identified by similarity to SP:P16095; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.913
HNE_1409
Pyridoxal-phosphate-dependent enzyme; Identified by match to protein family HMM PF00291.
 
 
 0.895
HNE_1212
Cys/Met metabolism PLP-dependent enzyme; Identified by match to protein family HMM PF01053.
  
 
 0.863
glyA
Serine hydroxymethyl transferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.846
serB
Phosphoserine phosphatase SerB; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488.
    
 0.835
hom
Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01113; match to protein family HMM PF01842; match to protein family HMM PF03447.
     
 0.820
Your Current Organism:
Hyphomonas neptunium
NCBI taxonomy Id: 228405
Other names: H. neptunium ATCC 15444, Hyphomonas neptunium ATCC 15444, Hyphomonas neptunium str. ATCC 15444, Hyphomonas neptunium strain ATCC 15444
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.