Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HNE_1997Peptidase, M20/M25/M40 family; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687. (395 aa)    
Predicted Functional Partners:
astA
Arginine N-succinyltransferase; Identified by match to protein family HMM PF04958.
 
   
 0.953
astB
Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).
 
     0.943
astD
Succinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
 
   
 0.913
maiA
Maleylacetoacetate isomerase; Identified by similarity to SP:O43708; match to protein family HMM PF02798; match to protein family HMM TIGR01262.
   
   0.776
HNE_1994
Putative methyltransferase; Identified by match to protein family HMM PF05175.
       0.762
argD
Acetylornithine/succinylornithine aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.603
HNE_1998
Identified by match to protein family HMM PF00691.
 
     0.558
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
    
 0.538
HNE_2336
Identified by match to protein family HMM PF00149.
 
     0.491
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.412
Your Current Organism:
Hyphomonas neptunium
NCBI taxonomy Id: 228405
Other names: H. neptunium ATCC 15444, Hyphomonas neptunium ATCC 15444, Hyphomonas neptunium str. ATCC 15444, Hyphomonas neptunium strain ATCC 15444
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