STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HNE_2136Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106. (245 aa)    
Predicted Functional Partners:
HNE_2133
Mandelate racemase/muconate lactonizing enzyme family protein; Identified by match to protein family HMM PF01188.
 
  
 0.985
HNE_2135
Identified by match to protein family HMM PF04909.
 
    0.887
HNE_2137
Identified by match to protein family HMM PF01557.
 
 0.850
HNE_2134
Oxidoreductase, aldo/keto reductase family; Identified by match to protein family HMM PF00248.
     0.839
HNE_3502
Oxidoreductase homolog.
  
     0.624
HNE_2132
Conserved hypothetical protein; Identified by match to protein family HMM PF05336.
 
  
 0.596
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 
 
 0.591
HNE_1820
Putative polyketide synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF07977; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 
 0.464
HNE_2203
Sulfatase domain protein.
  
   0.462
fabD
Malonyl CoA-acyl carrier protein transacylase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128.
 
 
 0.459
Your Current Organism:
Hyphomonas neptunium
NCBI taxonomy Id: 228405
Other names: H. neptunium ATCC 15444, Hyphomonas neptunium ATCC 15444, Hyphomonas neptunium str. ATCC 15444, Hyphomonas neptunium strain ATCC 15444
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