STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HNE_3328RNA polymerase sigma factor, ECF family; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa)    
Predicted Functional Partners:
HNE_3327
Putative anti-sigma factor, ChR family; Identified by similarity to SP:P40685; match to protein family HMM PF07883.
 
 
 0.997
HNE_1797
Conserved hypothetical protein; Identified by similarity to GB:BAB53726.1; match to protein family HMM PF01266.
 
  
 0.757
HNE_0281
RNA polymerase sigma-70 factor, ECF family; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.724
HNE_1796
Conserved hypothetical protein; Identified by match to protein family HMM PF07103.
 
   
 0.678
HNE_3329
Conserved hypothetical protein; Identified by similarity to PIR:AD3485.
       0.544
hfq
RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
 
   
 0.536
HNE_0219
Sigma factor regulatory protein, FecR/PupR family; Identified by match to protein family HMM PF04773.
 
 
 0.494
HNE_0094
Putative lipoprotein; Identified by similarity to GB:AAM41903.1.
  
 
 0.492
HNE_2941
Putative lipoprotein; Identified by similarity to GB:BAC94104.1.
 
   
 0.469
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
  
 0.455
Your Current Organism:
Hyphomonas neptunium
NCBI taxonomy Id: 228405
Other names: H. neptunium ATCC 15444, Hyphomonas neptunium ATCC 15444, Hyphomonas neptunium str. ATCC 15444, Hyphomonas neptunium strain ATCC 15444
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.