STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
soxRRedox-sensitive transcriptional activator SoxR; Identified by similarity to SP:P22538; match to protein family HMM PF00376; match to protein family HMM TIGR01950. (151 aa)    
Predicted Functional Partners:
HNE_3425
Identified by match to protein family HMM PF00903.
 
   
 0.885
merR
Mercuric resistance operon regulatory protein; Identified by similarity to SP:P13111; match to protein family HMM PF00376.
  
   
 0.663
HNE_1726
Transcriptional regulator, MerR family; Identified by similarity to SP:P13111; match to protein family HMM PF00376.
  
   
 0.655
HNE_1508
Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518.
   
 
 0.640
HNE_0085
DnaJ domain protein; Identified by match to protein family HMM PF00226.
  
 
 0.521
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.521
HNE_1302
Putative dnaJ protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556.
  
 
 0.521
glnA
Glutamine synthetase, type I; Identified by similarity to SP:P05457; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.
  
 
 0.469
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.451
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.421
Your Current Organism:
Hyphomonas neptunium
NCBI taxonomy Id: 228405
Other names: H. neptunium ATCC 15444, Hyphomonas neptunium ATCC 15444, Hyphomonas neptunium str. ATCC 15444, Hyphomonas neptunium strain ATCC 15444
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.